truSculpt was developed based on findings from the only published, peer-reviewed study demonstrating time-temperature dependency on
adipose cell viability.1,2 The in-vitro testing demonstrated 60 percent loss of cell viability following a sustained temperature of 45°C to
adipose cells for 3 minutes.
1 Walfre Franco, PhD, Amogh Kothare, MS, and David J. Goldberg, MD. Controlled Volumetric Heating of Adipose Tissue Using a Novel Radiofrequency Technology. Lasers in Surgery and Medicine 41:745-750 (2009) ; 2 Walfre Franco, PhD, Amogh Kothare, MS, Stephen J. Ronan, MD, FACS, Roy C. Grekin, MD and Timothy H. McCalmont, MD. Hyperthermic Injury to Adipocyte Cells by Selective Heating of Subcutaneous Fat with a Novel Radiofrequency Device: Feasibility Studies. Lasers in Surgery and Medicine 42:361-370 (2010)